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适合结核病诊断的创新性COVID-19治疗点诊断:一个范围审查

Lydia M L Holtgrewe¹, Sonal Jain¹, Ralitza Dekova¹

¹Department of Infectious Diseases and Tropical Medicine, Heidelberg University Hospital and Faculty of Medicine, Heidelberg University, 69120 Heidelberg, Germany.

Journal of clinical medicine

|October 16, 2024

概括

适应COVID-19护理点测试用于结核病诊断是可行的. 这次审查确定了66种潜在适用于外围结核病检测的SARS-CoV-2诊断设备,为全球结核病倡议提供了新的途径.

科学领域:

医学诊断医学诊断医学诊断
传染病研究传染病研究
公共卫生公共卫生

背景情况:

快速而准确的治疗点诊断对于解决全球结核病 (TB) 诊断差距至关重要.
在COVID-19诊断方面的进步为适应现有技术进行结核病检测提供了机会.
世界卫生组织 (WHO) 为理想的结核病诊断测试制定了目标产品概况 (TPP).

研究的目的:

系统地绘制商业上可用的POC SARS-CoV-2诊断测试,以潜在地适应结核病诊断.
评估这些测试与世卫组织TPP对外结核病测试设置的评估.
确定可用于全球结核病控制工作的有希望的诊断平台.

主要方法:

根据PRISMA-ScR指南进行了范围审查.
搜索了多个数据库和网站,查找POC抗原和分子SARS-CoV-2诊断测试,直到2022年11月.
关于性能,运营特征和监管状况的数据被提取并使用标准化得分卡进行评估.

主要成果:

审查了2003年的报告,其中有408份符合资格标准.
66个商业化SARS-CoV-2设备被确定为可能适应结核病诊断.
获得最高分的平台包括LumiraDx (抗原),Lucira Check-It (POC分子),Visby (近POC分子) 和Idylla (低复杂分子).

结论:

商用SARS-CoV-2诊断测试的多种范围显示出适应外围结核病测试的潜力.
利用这些技术可以支持全球结核病倡议,并应对诊断挑战.
促进合作和探索新的商业途径是改善结核病诊断的关键.

关键词:

在 COVID-19 疫情中,错过的诊断错过了诊断在护理点进行检测.快速诊断测试快速诊断测试快速诊断测试结核病是一种肺结核病.

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