探索炎症标记物和风险因素与心房炎的发展相关的房动的移除后的移除
Idris Yakut1, Hasan Can Konte1, Ozcan Ozeke2
1Department of Cardiology, Medipol Istanbul University, Istanbul 34815, Türkiye.
Journal of clinical medicine
|October 16, 2024
概括
心房后 (AF) 除性心膜炎 (PAP) 与更长的AF持续时间,洞穴支 (CTI) 除和睡眠呼吸暂停有关. 像SII,NLR和PLR这样的炎症标志物与PAP风险无关.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 炎症研究 炎症研究
背景情况:
- 在心房 (AF) 除后的术后并发症,特别是心膜炎 (PAP),需要进一步调查.
- 了解PAP的发病率和风险因素对于改善AF切除后患者的治疗结果至关重要.
研究的目的:
- 探索特定的炎症标志物与心房动后 (AF) 剥离性心膜炎 (PAP) 的发生之间的关联.
- 为了确定PAP的发病率,并确定相关的促成因素.
主要方法:
- 从2021年1月到2023年11月,对231名从2021年1月到2023年11月成功接受AF切除术的患者进行了回顾性队列研究.
- 对炎症标志物的分析:全身免疫炎症指数 (SII),中性粒细胞与淋巴细胞的比率 (NLR) 和血小板与淋巴细胞的比率 (PLR).
- 多变量后勤回归以确定绝对心周炎和任何心周炎的独立风险因素.
主要成果:
- 怀疑PAP的发生率为9.52%,确定PAP的发生率为6.06%.
- 确定的PAP的独立风险因素包括更长的AF持续时间和洞穴椎间盘 (CTI) 切除.
- 任何心膜炎 (疑似或确定的) 的独立风险因素是CTI切除和睡眠呼吸暂停.
结论:
- 延长AF持续时间,CTI切除和睡眠呼吸暂停被确定为PAP的重要风险因素.
- 研究的炎症标志物 (SII,NLR,PLR) 没有显示与PAP的关联.
- 需要进一步的研究来探索与PAP发展相关的其他潜在炎症标志物.
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