适应低FODMAP饮食在IBS患者和没有纤维肌痛:长期坚持和结果
Christian Lambiase1,2,3, Alessandra Rossi4, Riccardo Morganti5
1Gastrointestinal Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56124 Pisa, Italy.
Nutrients
|October 16, 2024
概括
同病性纤维肌痛对长期易怒肠综合征 (IBS) 症状的缓解的影响最小,适应低FODMAP饮食 (AdLFD). 在IBS患者中,对AdLFD的坚持仍然很高,无论纤维肌痛并发症情况如何.
科学领域:
- 胃肠病学 胃肠病学
- 饮食管理 饮食管理
- 伴随疾病的情况.
背景情况:
- 刺激性肠综合征 (IBS) 通常通过低FODMAP饮食 (LFD) 进行管理.
- 纤维肌痛经常与IBS共存,影响高达65%的病例.
- 适应LFD (AdLFD) 对于长期患者管理至关重要.
研究的目的:
- 评估并发性纤维肌痛对IBS患者AdLFD长期临床结果的影响.
- 为了评估IBS患者在有或没有纤维肌痛的情况下遵守AdLFD.
主要方法:
- 在AdLFD上注册的IBS患者有或没有纤维肌痛.
- 在基线 (T0) 和平均62.5个月的随访后 (T1) 评估患者.
- 使用了疾病严重程度,肠道习惯,心理状态和ADLFD遵守度的问卷.
主要成果:
- 在长期随访时,并发性纤维肌痛并没有显著影响IBS症状严重程度总得分.
- 纤维肌痛患者的基线焦虑和抑郁评分 (HADS) 较高.
- 在51名患者中有44名患者观察到AdLFD的长期良好坚持;所有患者的HADS得分都有所改善.
结论:
- 并发性纤维肌痛对AdLFD治疗IBS症状的长期有效性有很小的影响.
- 坚持AdLFD不受纤维肌痛的存在的影响.
- 在纤维肌痛患者的IBS治疗中,AdLFD是一种可行的非药物选择.
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