设计和组装一个小型导管成像系统,用于活体内心脏内镜成像
Walter Messina1, Lorenzo Niemitz1, Simon Sorensen1
1Biophotonics Group, Tyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.
Sensors (Basel, Switzerland)
|October 16, 2024
概括
这项研究引入了一种新型的芯片上尖端导管,配有微摄像头,用于在体内对心跳进行成像. 该设备成功捕获了清晰的内心图像,证明了其在先进的心脏诊断方面的潜力.
科学领域:
- 生物医学工程 生物医学工程
- 医疗成像医学成像
- 心血管技术的心血管技术
背景情况:
- 在活体中对跳动的心脏进行成像,由于血液遮蔽了视线,因此存在挑战.
- 现有的内镜技术在捕捉心室内清晰图像的能力上是有限的.
- 最少侵入性可视化对于准确的心脏诊断和手术导航至关重要.
研究的目的:
- 设计和制造一种新的芯片在尖端导管,用于在体内对跳动的心脏进行成像.
- 为了证明这种导管平台的医疗实用性和机械强度.
- 介绍组装说明,并讨论微型内镜原型的系统要求.
主要方法:
- 开发一个结合微镜头和光纤的芯片在尖端导管.
- 使用盐水冲洗系统来清除视野中的血液.
- 导管导航在光学指导下通过导管导入到心脏各个位置.
- 从心房内隔膜,左心房和左心室获取图像.
主要成果:
- 成功制造并演示了一种新的芯片在尖端导管系统.
- 内心壁的清晰的体内图像被捕获在一个跳动的猪心脏中.
- 导管平台表现出机械强度,并成功导航到目标心脏位置.
- 首次在跳动的心脏体内获得体内内图像的内镜图像.
结论:
- 这种新型的芯片在尖端导管为体内心脏成像提供了可行的解决方案.
- 这项技术对光学诊断技术,手术指导和心脏病学临床导航具有重大潜力.
- 微型原型的进一步开发得到了讨论的挑战和系统要求的支持.
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