饮食发酵蓝粉补充剂改善了小肠道屏障功能,并调节了老年产母的菌群
Binghua Qin1,2,3, Zhihua Li1, Qian Zhu1,3
1Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutrition Physiology and Metabolic Processes, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.
Animals : an open access journal from MDPI
|October 16, 2024
概括
发酵蓝粉末 (FBP) 通过增强肠道形态和改变肠道微生物群,改善了老年产母的肠道屏障功能. 这种食补充剂对肠道健康和微生物组成有积极的影响.
科学领域:
- 动物营养 动物营养
- 肠道健康 肠道健康
- 微生物组研究 微生物组研究
背景情况:
- 产母的老化会损害肠道屏障功能,影响整体健康和生产力.
- 饮食干预对于维持禽类的肠道完整性和微生物平衡至关重要.
- 发酵蓝粉末 (FBP) 是动物料中生物活性化合物的潜在来源.
研究的目的:
- 为了研究食发酵蓝残渣 (FBP) 对老年产母的肠壁功能的影响.
- 分析 FBP 补充剂对产母的 cecal 微生物组合和功能的影响.
- 探索FBP诱导的肠道微生物组变化和肠道屏障基因表达之间的相关性.
主要方法:
- 一项养试验涉及320只老年产卵母,这些母被随机分配到对照或FBP补充饮食 (0.25%,0.5%,1.0%).
- 评估肠道形态 (小高度,表面积) 和基因表达 (Mucin-2,IL-4,IL-13).
- 使用测序和微生物功能预测的Cecal微生物组分析,以及与肠道健康参数的相关性分析.
主要成果:
- 补充FBP (0.25%-0.5%) 改善了阴小的高度和表面积,以及阴小的高度.
- 在FBP (0.5%-0.5%) 观察到在真和结核中Mucin-2表达的升调.
- FBP (0.5%-1.0%) 增加了盲体中的Prevotella丰度,并改变了微生物代谢途径.
结论:
- 饮食发酵蓝果汁可以有效地增强老年产母的肠道屏障功能.
- 补充FBP可以积极调节肠道形态,与屏障相关的基因表达和肠道微生物群组成.
- 这些发现表明FBP是一种有前途的料添加剂,可以改善老年家禽的肠道健康.
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