豆蛋白水解盐与曼诺斯和艾卢洛斯结合的生物活性
Artorn Anuduang1, Sakaewan Ounjaijean1, Rewat Phongphisutthinant2
1Research Institute for Health Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Foods (Basel, Switzerland)
|October 16, 2024
概括
大豆蛋白水解酸与曼诺糖 (SPHM) 和糖 (SPHA) 的梅拉德反应结合物显示出增强的抗氧化剂,抗胰腺脂酶和血管酶转化酶 (ACE) 抑制活性. 这些发现表明功能性食品和补充剂的潜在应用.
科学领域:
- 食品科学 食品科学 食品科学
- 生物化学 生物化学
- 营养保健品 营养保健品
背景情况:
- 通过梅拉德反应的非酶联结增强了的生物活性.
- 豆蛋白水解盐 (SPH) 是生物活性的来源.
- 曼诺酸和酸是罕见的糖,具有潜在的功能性质.
研究的目的:
- 合成和评估SPH与曼诺 (SPHM) 和 (SPHA) 结合的生物活性.
- 评估SPHM和SPHA的抗氧化,抗胰腺脂酶,BSA变性抑制和抗ACE活动.
主要方法:
- 梅拉德反应被用来将SPH与曼诺和氨结合起来.
- 在实验室中进行了包括DPPH,FRAP,胰腺脂酶抑制,BSA变性抑制和ACE抑制在内的测试.
- 活动与控制和单个组件进行了比较.
主要成果:
- SPHM和SPHA表现出显著增强的抗氧化活性 (DPPH和FRAP测定).
- 这两种结合物都抑制了BSA变性,SPHM显示出更高的疗效.
- 与SPHM相比,SPHA表现出优越的胰腺脂酶抑制.
- SPHM,SPHA和罕见的糖类显示出显著的 ACE 抑制活性,相当于Enalapril.
结论:
- SPHM和SPHA具有多种生物活性特性,包括抗氧化剂,抗脂酶和ACE抑制.
- 这些合物显示出作为食品和保健补充剂的功能成分的希望.
- 梅拉德反应是提高大豆蛋白水解酸的生物活性的一种有效策略.
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