对患有先天性缺陷的儿童和儿科急性腹腔紧急情况的不同输血要求的评估
Alin Ionescu1,2, Alexandra Mihăilescu3, Adela Chiriță-Emandi3
1Center for Preventive Medicine, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Diagnostics (Basel, Switzerland)
|October 16, 2024
概括
患有先天性形 (CMs) 的儿科患者在手术前输血时比患有急性腹部 (AA) 的儿科患者更好地纠正贫血. 推量身定制的输血策略,以获得最佳的儿科外科护理.
科学领域:
- 儿科血液学 儿科血液学
- 手术性贫血管理的管理
- 遗传性缺陷 遗传性缺陷是一种先天性缺陷
背景情况:
- 在小儿外科手术患者中,术前贫血很常见.
- 先天性形 (CMs) 和急性腹部 (AA) 代表了具有不同临床需求的不同患者群体.
- 术前输血在纠正贫血方面的疗效可能在这些儿科患者队列之间有所不同.
研究的目的:
- 为了比较手术前输血在纠正贫血的有效性,在儿童患者的CMs与那些与AA.
- 根据潜在的病理学研究输血反应的潜在差异.
- 为儿童手术患者提供最佳输血策略的信息.
主要方法:
- 对107名小儿科患者进行了回顾性分析,这些患者接受了手术前输血治疗贫血.
- 血红蛋白 (HGB),血红素 (HCT) 和红细胞计数 (RBC) 在入院时,输血后48小时和出院后的比较.
- 使用学生的t测试,皮尔森相关性和千平方测试来比较CM和AA组之间的结果的统计分析.
主要成果:
- 与AA患者相比,患有CM的儿童的基线HGB和HCT水平显著更高.
- 输血后,CM患者的HGB增加更大,特别是那些中枢神经系统缺陷的患者.
- 贫血纠正在患有AA的儿童中不那么明显,腹膜炎病例显示HGB增加较小.
结论:
- 患有先天性形的儿科患者对手术前输血的反应比患有急性腹部疾病的儿童更有效.
- 研究结果表明,需要根据潜在的疾病量身定制的不同输血策略.
- 优化输血方法可以提高儿科手术的临床结果和资源利用率.
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