相关实验视频
Updated: Jun 10, 2025
07:01
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
21.0K
一个分析比较的乳头甲状腺癌患者表现出或没有格雷夫斯病的分析比较
Zeynel Abidin Sayiner1, Yagmur Yatkin Keles2, Sadettin Ozturk1
1Department of Endocrinology and Metabolism, Gaziantep University Faculty of Medicine, Gaziantep, Türkiye.
Sisli Etfal Hastanesi tip bulteni
|October 16, 2024
概括
在患有乳头甲状腺癌 (PTC) 的患者中,格雷夫斯病 (GD) 与较小的瘤和较少的多焦点性有关. 这种共存可能表明GD的PTC患者的预后更好.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 格雷夫斯病 (GD) 和乳头甲状腺癌 (PTC) 之间的关系尚不清楚.
- 了解临床病理差异对于患者管理至关重要.
研究的目的:
- 为了比较PTC患者的临床病理特征,同时存在格雷夫斯病和不存在格雷夫斯病.
- 调查GD在PTC中的潜在预后影响.
主要方法:
- 对239名经过全甲状腺切除术的PTC患者进行了回顾性队列研究.
- 结核病患者和没有结核病患者之间的年龄,阶段,瘤大小,复发风险和其他特征的比较.
主要成果:
- 41%的PTC患者同时存在GD.
- 患有GD的PTC患者的瘤直径显著更小 (1.45±1.28厘米对比1.81±1.34厘米),多焦点疾病的发病率更低.
- 经典的PTC亚型在没有GD的患者中更为普遍 (39%vs25.7%).
结论:
- 复发的风险似乎类似于带有或没有GD的PTC.
- 较小的瘤大小和较少的多焦点性在GD-PTC共存可能表明有利的预后.
相关概念视频
00:59The Parathyroid Glands
1.9K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
1.9K
01:20Synthesis and Regulation of Thyroid Hormones
4.3K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.3K