在乳头甲状腺癌中右侧甲状腺侧侧侧淋巴结转移的风险因素
Ozan Caliskan1, Isik Cetinoglu1, Nurcihan Aygun1
1Department of General Surgery, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
概括
在乳头甲状腺癌 (PTC) 中,右侧侧侧侧侧侧淋巴结 (RPTPLLN) 的转移与前中性淋巴结的转移有关. 考虑RPTPLLN剖析当中介性转移存在时.
科学领域:
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 乳头甲状腺癌 (PTC) 的发病率正在上升,需要仔细的手术规划,以尽量减少并发症.
- 复发性喉神经 (RLN) 在解剖学上划分了右侧腹腔淋巴结 (RPTLN) 区域,在剖析过程中对神经构成风险.
- 前侧淋巴结与RLN特别接近,增加了神经损伤的风险.
研究的目的:
- 在患有PTC的患者中,识别右侧腹后侧淋巴结 (RPTPLLN) 中转移的风险因素.
- 引导手术程度,减少甲状腺癌治疗期间的手术并发症.
主要方法:
- 对55名PTC患者进行回顾性分析,这些患者接受了中央部解剖 (CLND) 或CLND加侧部解剖.
- 对术前成像和术后病理发现的评估.
- 统计分析,包括单变量和多变量分析,以确定重大风险因素.
主要成果:
- 在23.6%的患者中观察到RPTPLLN转移.
- 统一分析确定了甲状腺外延伸,淋巴血管入侵和甲状腺转移在中间前 (RPTAMLN) 和对侧侧侧侧淋巴结中都是显著的.
- 多变量分析显示,只有RPTAMLN转移是RPTPLLN转移的显著独立预测因子 (p=0.035).
结论:
- 在PTC患者中,RPTAMLN转移是RPTPLLN转移的重要风险因素.
- 在接受CLND的右叶瘤患者中,应考虑对RPTLN进行正式解剖,特别是后侧解剖 (PLD),特别是如果存在或怀疑RPTAMLN转移.
- 如果中外组织的冷病理是负面的,则可以省略PLD,但建议仔细考虑.
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