用于计算机断层扫描和X射线成像幻影的3维打印和造材料的表征
B E Yunker1,2, A Holmgren3, K F Stupic1
1Physical Measurement Laboratory, National Institute of Standards and Technology, Boulder, CO 80305, USA.
概括
研究人员测试了101个聚合物样本,用于医疗成像幻影中的组织模拟器. 一些3D打印材料看起来很有前途,因为X射线模仿脂肪和肌肉组织.
科学领域:
- 医疗成像医学成像
- 材料科学 材料科学 材料科学
- 生物材料是一种生物材料.
背景情况:
- 医疗计算机断层扫描 (CT) 系统需要使用成像幻影进行校准和验证.
- 3D打印的进步为创造新,仿生和几何精确的幻影提供了潜力.
- 识别具有特定X射线衰减特性的合适材料对于幻影发展至关重要.
研究的目的:
- 测量各种聚合物化合物的X射线线性衰减系数.
- 用3D打印和造技术识别CT和X射线幻影的潜在组织模拟材料.
- 为了比较聚合物样本的衰减特性与已确定的人类组织值.
主要方法:
- 测试了101个标准化聚合物样本,包括,聚氨和热塑性塑料,在固化形式.
- 使用商用微型CT成像系统进行40 kVp至140 kVp的能量范围内的测量.
- 绘制的X射线线性减弱系数与人类组织值的样本,包括错误条.
主要成果:
- 在测试的聚合物样本中,X射线线性衰减系数差异很大.
- 一部分材料的衰减值与已建立的人体组织模拟器重叠.
- 20个3D打印材料和一个可造的聚氨模仿脂肪 (尼龙,PMMA),而5个3D打印材料模仿肌肉 (水).
结论:
- 某些聚合物,特别是适合3D打印的聚合物,在幻影应用中具有X射线组织模拟器的潜力.
- 这项研究为选择用于制造精确和仿生成像幻影的材料提供了有价值的数据.
- 进一步的研究可以利用这些发现来开发用于CT和X射线系统表征的先进幻象.
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