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Updated: Jun 10, 2025

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基本代谢率介导肠道微生物群和骨关节炎之间的因果关系:一个双步双向的门德尔随机化研究

Jiachen Li1,2, Jianhui Liang1,2, Yang Liu1

  • 1Department of Orthopedics, Shenzhen Second People's Hospital/First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.

Frontiers in microbiology
|October 16, 2024
PubMed
概括

特定的肠道细菌,如Actinobacteria,可能会降低骨关节炎 (OA) 的风险. 基本代谢率 (BMR) 调解了这种联系,这表明肠道健康可以预防OA.

关键词:
门德尔的随机化基本代谢率基本代谢率我们的肠道微生物群.调解调解是指调解的方式.骨关节炎是一种关节炎.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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