使用Bio-Oss®原蛋白治疗内缺陷的最小侵入性治疗的效果
Kashish Luthra1, Vandana Sarangal1, Sahib Tej Singh1
1Department of Periodontics, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, India.
Bioinformation
|October 16, 2024
概括
结合微创手术技术 (MIST) 的Bio-Oss®原异质移植显著改善了内缺陷中的牙周健康. 这种再生方法在治疗慢性牙周炎时,与单独使用MIST相比,显示出更好的结果.
科学领域:
- 牙周病学 牙周病学
- 恢复性牙科 恢复性牙科
- 生物材料是一种生物材料.
背景情况:
- 内骨缺陷是慢性牙周炎的一个常见并发症.
- 最少侵入性外科技术 (MIST) 提供了一种不那么侵入性的牙周再生方法.
- 生物Oss®原蛋白是一种来自牛的异种移植,是骨再生的潜在材料.
研究的目的:
- 为了评估Bio-Oss®原异构体移植与MIST结合用于治疗内缺陷的疗效.
- 为了比较MIST与Bio-Oss®原蛋白与单独MIST的再生结果.
主要方法:
- 一项随机对照试验,涉及30名患有慢性牙周炎和骨内缺陷的患者.
- 参与者被分为两组:A组 (MIST + Bio-Oss®原蛋白) 和B组 (仅MIST).
- 牙周参数包括斑块指数,牙指数,探针口袋深度,临床附着水平和骨内缺陷填充在3个月和6个月后被评估.
主要成果:
- 这两组在牙周参数上均显著改善.
- 与B组相比,A组 (MIST + Bio-Oss®原) 在内缺陷填充和临床附着水平方面显示出明显更好的结果.
- 两组之间斑块或牙指数没有显著差异.
结论:
- 当与MIST一起使用时,Bio-Oss®原异构体移植是一种有效的再生治疗,用于慢性牙周炎中内缺陷的治疗.
- 与单独使用MIST相比,Bio-Oss®原蛋白和MIST的组合在牙周再生方面提供了卓越的结果.
- 这种方法有望改善患有牙周内骨缺陷的患者的临床结果.
相关概念视频
01:29Bone Formation by Intramembranous Ossification
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
01:27Fractures: Bone Repair
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
01:31Bone Remodeling and Repair
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...