维生素E适用于非酒精性脂肪性肝病患者
Hongzhu Wen1, Hongyong Deng2, Lili Yang3
1Department of Gastroenterology, Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
The Cochrane database of systematic reviews
|October 16, 2024
概括
补充维生素E可能对代谢功能障碍相关的脂肪性肝病 (MASLD) 提供最小的益处,对死亡率和不良事件的影响非常不确定. 虽然它可能会略微降低肝酶,但其临床影响仍然未知.
科学领域:
- 肝病学和胃肠病学 肝病学和胃肠学
- 营养科学 营养科学
- 临床试验和基于证据的医学
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD),以前称为NAFLD,是一种普遍存在的全球性肝病,治疗方法不理想.
- 氧化应激是MASLD病变发生的关键因素,维生素E正在研究其潜在的益处.
- 目前对维生素E在MASLD患者的疗效和安全性的了解有限.
结论:
- 证据不足以确定维生素E对MASLD患者的长期益处或危害.
- 需要进一步的研究来澄清维生素E在管理MASLD及其相关肝酶水平中的作用.
- 与维生素E一起观察到的肝酶轻微减少的临床影响仍未确定.
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