低碳水化合物饮食在1型糖尿病的年轻人中被证明是有效和安全的:一项随机试验
Neriya Levran1,2,3,4, Noah Levek1,2, Noah Gruber1,5
1Paediatric Endocrine and Diabetes Unit, Edmond and Lily Safra Children's Hospital, Chaim Sheba Medical Centre, Ramat-Gan, Israel.
Acta paediatrica (Oslo, Norway : 1992)
|October 16, 2024
概括
低碳水化合物和地中海饮食都改善了1型糖尿病年轻人的血糖控制. 两种饮食都没有增加风险,在治疗糖尿病方面显示出相似的安全性和有效性.
科学领域:
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
- 营养科学 营养科学
背景情况:
- 低碳水化合物 (LC) 饮食在管理代谢健康方面越来越受欢迎.
- 青少年和青少年的1型糖尿病 (T1D) 需要仔细的血糖管理.
- 对比饮食干预措施对于优化年轻人群T1D护理至关重要.
研究的目的:
- 为了比较LC和地中海 (MED) 饮食对血糖和代谢参数的影响.
- 评估这些饮食在患有T1D的青少年和青少年的安全性和有效性.
主要方法:
- 一个为期六个月的,开放的,随机的试验,涉及40名参与者.
- 参与者被分配到LC或MED饮食中.
- 使用持续血糖监测 (CGM) 和HbA1c水平评估的血糖结果.
主要成果:
- 两种LC和MED饮食都改善了血糖范围的时间 [3.9-10.0 mmol/L].
- 与MED饮食相比,LC饮食显示高血糖症 (>13.9 mmol/L) 的时间减少更大 (p=0.005).
- 两组HbA1c均有改善 (p=0.02),低血糖 (<3.0 mmol/L) 或BMI Z-score和脂质的变化没有显著差异.
结论:
- 无论是LC还是MED饮食,都安全有效地改善了T1D年轻人的血糖控制.
- 两种饮食都没有与降血糖或心血管风险因素的增加有关.
- 饮食选择可以根据个体需求量身定制,同时保持可比的健康结果.
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