与代谢 (功能障碍) 相关的脂肪肝疾病指标和对肝脏研究的贡献
Maito Suoh1, Saeed Esmaili1, Mohammed Eslam1
1Storr Liver Centre, The Westmead Institute for Medical Research, Westmead Hospital and The University of Sydney, 176 Hawkesbury Rd, Westmead, NSW, 2145, Australia.
Hepatology international
|October 16, 2024
概括
代谢 (功能障碍) 相关的脂肪肝疾病 (MAFLD) 的定义对肝脏研究产生了重大影响,显示出更多的出版物和更好的诊断性能. 这种重新定义促进了临床实用性和在管理心脏代谢疾病方面的全球合作.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢障碍 代谢障碍 代谢障碍
- 图书统计学 图书统计学
背景情况:
- 2020年国际共识将非酒精性脂肪性肝病 (NAFLD) 重新定义为与代谢 (功能障碍) 相关的脂肪性肝病 (MAFLD).
- 研究界的反应和这种重新定义的影响需要客观评估.
研究的目的:
- 分析MAFLD定义的研究影响.
- 评估MAFLD研究自成立以来的关键主题和趋势.
主要方法:
- 从2020年到2023年10月在PubMed,科学网和Scopus上对MAFLD出版物的系统文献搜索.
- 分析出版物指标,包括数量,期刊,作者国家,关键词和引用.
主要成果:
- 在434个期刊上发表了1469篇MAFLD论文,显示出稳定的增长.
- 研究重点从重新定义讨论转移到临床表征和代谢功能障碍.
- 与NAFLD相比,MAFLD标准显示出对肝脏和肝外结局的预测优越.
- 出版物来自99个国家,表明了强大的全球合作.
结论:
- MAFLD的定义对肝脏研究产生了相当大的国际影响.
- MAFLD因其临床实用性,改善患者管理和心脏代谢障碍研究中的作用而得到认可.
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