在基于人口的队列中,功能性体力障碍的波动. 根据 DanFunD 的研究
Signe U Schovsbo1, Line L Kårhus1, Anne A Bjerregaard1
1Center for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
PloS one
|October 16, 2024
概括
功能性体力障碍 (FSD) 显示出显著的波动,近50%的缓解率和综合征之间的高互换性超过五年在一般人群中.
科学领域:
- 精神病学和一般医疗
- 流行病学 流行病学
- 身体形状障碍 研究 研究 研究
背景情况:
- 功能性体力障碍 (FSD) 缺乏明确的定义,阻碍了发生率研究.
- 在一般人群中,关于FSD缓解,持久性和综合征可互换性的知识有限.
研究的目的:
- 在五年时间内评估各种功能性体力障碍 (FSD) 的自然过程.
- 在一般人群中调查FSD的发病率,缓解和可互换性.
主要方法:
- 一项为期5年的随访研究 (丹麦功能障碍研究-DanFunD) 对5,738名随机选择的成年人进行了随访.
- 经过验证的调查问卷评估了身体痛苦综合征 (BDS) 和四种功能性体力综合征 (FSS):易怒肠 (IB),慢性疲劳 (CF),慢性广泛疼痛 (CWP) 和多重化学敏感性 (MCS) 在基线和随访时.
主要成果:
- 身体应急综合征 (BDS) 和功能性体征综合征 (FSS) 的五年发病率约为11%.
- 个人FSS发生率从多重化学敏感性 (MCS) 的0.8%到慢性疲劳 (CF) 的5.7%不等.
- BDS和FSS的缓解率接近50%,在单个FSS之间观察到很高的可互换性 (15.0%23.4%).
结论:
- 功能性体力障碍 (FSD) 随着时间的推移表现出显著的波动,其特点是综合征之间具有很高的可互换性.
- 未来的研究需要大规模的,以人口为基础的群体,具有精确的FSD划界,以了解这些复杂的条件.
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