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Updated: Jun 10, 2025

Generation of Human Chimeric Antigen Receptor Regulatory T Cells
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Generation of Human Chimeric Antigen Receptor Regulatory T Cells

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人类OX40L-CAR-Tregs针对激活的抗原呈现细胞,并控制T细胞的全活性

Xianliang Rui1, Francesca Alvarez Calderon1,2,3, Holly Wobma3,4

  • 1Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA.

Science translational medicine
|October 16, 2024
PubMed
概括

针对OX40连体的工程调节性T细胞 (Tregs) 显示出增强的稳定性和疗效,用于治疗自身免疫和非免疫疾病.

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