高分辨率功率电子喷雾电离化离子移动性光谱仪 基于富里埃解卷法 解卷多重复合法
Binwang Yang1, Zhixiong Ye1, Feiyu Lu1
1College of Chemical Engineering, Xiangtan University, Xiangtan 411105, China.
Analytical chemistry
|October 16, 2024
概括
里叶解卷 (FD) 提高了离子移动性光谱 (IMS) 解析能力,用于分析非挥发性化合物. 这种技术可以通过使用电喷离子化 (ESI) -IMS改善类似化合物的分离,而不会增加仪器尺寸.
科学领域:
- 分析化学 分析化学
- 频谱测量是一种光谱测量.
背景情况:
- 漂流管离子流动性光谱 (IMS) 的分辨能力对于分离结构相似的非挥发性化合物至关重要.
- 电子喷雾电离 (ESI) -IMS提供高灵敏度,但对于复杂的混合物,需要增强的分辨能力.
研究的目的:
- 调查里埃解卷 (FD) 复合技术,以提高大气压的ESI-IMS分析性能.
- 提高ESI-IMS的解析能力和信号噪声比.
主要方法:
- 使用Tyndall-Powell离子快门来实现5μs相当的离子门开口宽度.
- 采用里叶解卷 (FD) 复合与漂流管离子移动性光谱 (IMS).
- 评估了使用Rhodamine 6G,SDS,甲环素,氧环素和拉克托巴的技术.
主要成果:
- 在12厘米的漂移长度和10千伏的漂移电压下,达到高分辨率功率 (R_P) 高达170.
- 使用FD-ESI-IMS.成功分离具有相似离子流动性的混合物.
- 在不延长漂移长度的情况下,展示了更好的分辨率和信号噪声比.
结论:
- 里叶解卷 (Fourier deconvolution,FD) 是一种有效的方法,可以显著提高ESI-IMS的解析能力.
- FD-ESI-IMS能够更好地分离含有具有类似离子流动性的化合物的复杂混合物.
- 该技术提供了一种方便的方法来提高分析性能,而不需要更大的仪器仪表.
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