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Updated: Jul 6, 2026

Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay
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自然产品结合的金复合物的研究进展,作为潜在的抗瘤剂

Meiyu Wang1, Fuwei Li2, Zhaoran Wang2

  • 1Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, PR China.

European journal of medicinal chemistry
|October 16, 2024
PubMed
概括

将天然产品与金复合物的结合提供了一个有希望的策略,以提高抗癌效果,并克服与传统金药物相关的耐药性问题.

关键词:
抗瘤剂是一种抗瘤剂.黄金复合体的黄金复合体.自然产品是天然产品.金复合体是一种金复合体.

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Phase II Reactions: Miscellaneous Conjugation Reactions

Phase II biotransformations are detoxification mechanisms that conjugate xenobiotics with endogenous substances, neutralizing their toxicity.
A key example involves the conjugation of cyanide ions, which impair cellular respiration and alter hemoglobin into non-oxygen-carrying cyanmethemoglobin. To neutralize this threat, a sulfur atom from thiosulphate is transferred to the cyanide ion, catalyzed by the enzyme rhodanese, resulting in an inactive compound called thiocyanate. The production of...