改善冠状动脉疾病老年人药物坚持的教育计划:系统性审查和元分析
Mengqi Xu1, Suzanne Hoi Shan Lo1, Elaine Yi Ning Miu1
1The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.
International journal of nursing studies
|October 16, 2024
概括
教育计划显著改善了干预后两到六个月冠状动脉疾病的老年人的药物坚持. 需要进一步的研究来确认一个月内的影响和长期影响.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 冠状动脉疾病 (CAD) 是全球主要的死亡原因.
- 最佳的药物坚持对于CAD管理至关重要,但对于老年人来说是不理想的.
- 建议开展教育计划,以提高这一群体的药物坚持,但证据有限.
研究的目的:
- 系统地评估教育计划对CAD的老年人药物坚持的影响.
主要方法:
- 一个系统的审查和随机对照试验 (RCTs) 的元分析发表到2024年1月.
- 搜索了12个英语和5个中文数据库,寻找涉及患有CAD的老年人 (≥60岁) 的RCT.
- 使用Cochrane风险偏见工具v2评估研究质量,使用GRADE评估证据确定性.
主要成果:
- 其中包括六个RCT. 教育计划显著改善了干预后2-6个月的药物坚持 (SMD:1.13;95% CI:0.33-1.94;P=0.006;中等确定性).
- 在干预后一个月内,没有发现对坚持的显著影响 (SMD:2.18;95% CI:-1.22-5.58;P=0.21;低确定性).
- 叙事综合表明,在六个月的时间内,对CAD的理解和药物管理能力的潜在改善.
结论:
- 教育计划在改善干预后2-6个月内患有CAD的老年人服用药物的有效性方面表现出显著的效果.
- 这些计划在一个月内产生的影响仍然是不确定的,长期影响需要进一步调查.
- 建议设计具有理论框架和精细组件的程序,以解决复杂的健康需求.
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