一种基于脂质的阿育吠陀多草药配方的产品开发和特征:Kalyanaka Ghrita
Yashika Singh1, Amzad Ali Ansari2, Rajendra Prasad Sharma1
1Department of Rasa Shastra and Bhaishajya Kalpana, National Institute of Ayurveda, Deemed to be University (De-Novo), Jaipur, Rajasthan, India.
Journal of Ayurveda and integrative medicine
|October 16, 2024
概括
标准化Kalyanaka Ghrita (KG) 制造确保了治疗精神疾病的一致质量. 这项研究确立了KG生产的验证程序,在各批次中产生一致的结果.
科学领域:
- 艾尔韦达药理学 艾尔韦达药理学
- 植物化学 植物化学
- 传统医学标准化标准化
背景情况:
- 卡里亚纳卡格里塔 (KG) 是一种多草药配方,用于治疗精神障碍,如精神分裂症和.
- KG 含有 28 种不同的药用植物的提取物.
研究的目的:
- 开发和验证卡利亚纳卡格里塔 (KG) 的标准制造程序.
- 确保在三个生产批次中确保工艺统一性和遵守质量标准.
主要方法:
- 根据阿育吠陀的原则 (Ashtanga Hrudya,印度的阿育吠陀公式) 准备KG批量.
- 记录了过程参数 (温度,持续时间).
- 进行了体感,物理化学,GCMS指纹和HPLC分析 (黄素,切布拉基酸).
主要成果:
- 平均KG产量为83.41%,采用了三天的加热过程 (平均. 20.35小时,66-101°C) 的时间.
- 在各批次中观察到一致的感官和物理化学概况.
- 安全参数在允许的范围内.
结论:
- 药物标准化KG对于其生物和化学表征至关重要.
- 建议使用粗粉状的原料,并在三天内将其加热到Madhyama Paka阶段.
- 这项研究为未来的KG制造标准和研究提供了基础.
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