痴呆症老年人死亡率相关因素:一项前性观察性研究
Yiğitcan Boran1, Yusuf Ali Altuncı1, Sercan Yalçınlı1
1Ege University Faculty of Medicine, Department of Emergency Medicine, Izmir, Turkey.
概括
在老年人呈现给急诊室的 Delirium 与显著的 3 个月死亡率有关. 关键的危险因素包括有 Delirium 的病史,活跃的癌症和呼吸率升高.
科学领域:
- 老年医学 老年医学
- 神经精神病学是一种神经精神病学.
- 临界护理医学 临界护理医学
背景情况:
- 妄想是一种严重的神经精神综合征,在临床环境中很常见,与高发病率和死亡率有关.
- 了解导致痴呆相关死亡的因素对于改善患者的治疗结果至关重要.
- 与狂妄症死亡率相关的具体因素仍未得到很好的定义.
研究的目的:
- 为了确定影响老年痴呆症患者3个月死亡率的因素.
- 调查患有妄想症的急诊室 (ED) 人群中死亡率的预测因素.
主要方法:
- 前性研究设计.前性研究设计.
- 使用简要的混评估方法 (bCAM) 进行 Delirium 查.
- 统计分析包括曼-惠特尼U,奇平方测试,斯皮尔曼相关性和多变量逻辑回归来确定3个月死亡率的风险因素.
主要成果:
- 总共有243名患者被纳入; 56.4%的患者经历了3个月的死亡率.
- 与死亡风险增加显著相关的因素包括先前的妄想史 (OR 3.32),活跃的恶性瘤 (OR 3.49) 和增加的呼吸速率 (OR 1.18).
- 增加的平均动脉压 (MAP) (OR 0.98) 和体温 (OR 0.48) 与死亡风险降低有关.
结论:
- 较高的呼吸速率,较低的MAP,较低的体温,活跃的恶性瘤和先前的妄想史是ED中妄想的老年人死亡风险增加的指标.
- 这些发现突出了风险分层和老年痴呆患者管理的关键因素.
- 早期识别这些风险因素可能会改善患者的治疗结果并降低死亡率.
更多相关视频
06:23The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
Published on: October 13, 2016
32.2K
12:18A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
7.5K
相关概念视频
Dementia
97
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
97
Cognitive Development During Adulthood
65
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
65
Alzheimer's Disease: Overview
449
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
449
Longitudinal Research
11.9K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
11.9K
