对HLA-DPB1氨基酸多态的种群遗传剖析以推断选择选择

Steven J Mack1, Richard M Single2, Owen D Solberg3

  • 1Department of Pediatrics, University of California, San Francisco, Oakland, CA, United States.

Human immunology
|October 16, 2024
PubMed
概括

均衡选择在氨基酸水平上塑造人类白细胞抗原 (HLA) DPB1的多样性,而不是等位基水平. 这项研究揭示了在强大的平衡选择下特定的氨基酸位置,为免疫系统进化提供了新的见解.

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