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在青少年开始精神性厌食症30年后,病前体重参数可以预测BMI吗?
Peter Goldberg1, Sandra Rydberg Dobrescu2, Carina Gillberg2
1Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden.
Eating behaviors
|October 16, 2024
概括
在青少年精神性厌食症 (AN) 发生30年后,没有幼儿时期的人类测量因素预测成人BMI. 儿童期 AN可能会扰乱长期的体重轨迹,影响成年人体质指数 (BMI).
科学领域:
- 儿科内分泌学 儿科内分泌学
- 营养精神病学 营养精神病学
- 纵向健康研究 纵向健康研究
背景情况:
- 青少年精神性厌食症 (AN) 是一种严重的饮食障碍,具有潜在的长期健康后果.
- 了解影响青少年AN后长期体重指数 (BMI) 轨迹的因素对于临床管理至关重要.
- 以前的研究还没有明确确定成年人BMI的先发性预测因子,这些人有青少年AN史.
研究的目的:
- 调查婴儿和儿童时期的特定人体测量是否可以预测青少年AN开始30年后的BMI.
- 为了比较青少年AN患者与匹配的健康对照组之间的预测关系.
主要方法:
- 研究了一组51名青少年发病AN (1985年发现,瑞典) 患者和一组匹配的健康对照组.
- 人类测量数据,包括出生时的体重指数和童年时最高的BMI Z-score,从出生和学校记录中收集.
- 使用线性回归和多变量分析来评估患病前人类学变量与30年随访时的BMI之间的关联.
主要成果:
- 在青少年AN发作30年后,评估的先发性人体预测指标和BMI之间没有发现显著的相关性.
- 在健康的对照组中,出生时的体重指数在18年 (r=0.36,p=0.015) 和30年随访期间 (r=0.32,p=0.034) 显著预测了BMI.
- 这些发现表明,与一般人群相比,患有青少年AN史的个体的BMI轨迹有差异.
结论:
- 患病前的人类测量因素似乎不是长期BMI结果的可靠预测因素,在成年人有青少年AN的历史.
- 青少年AN的经历可能会改变BMI的自然轨迹,可能导致成年人体重状况低于预期.
- 这些见解可以为临床实践提供信息,有助于管理患者对AN恢复后体重增加的担忧.
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