相关实验视频

Updated: Jun 10, 2025

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

评估确定中风相关肺炎后死亡时间的生理变量

Amit K Kishore^1,2, Calvin Heal³, Anna Onochie-Williams¹

¹Greater Manchester Comprehensive Stroke Centre, Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance, Salford Royal, Salford, UK.

Cerebrovascular diseases (Basel, Switzerland)

|October 16, 2024

概括

较高的呼吸率和国家早期预警分数 (NEWS) 2与中风相关肺炎 (SAP) 患者的死亡率有关. 这些发现突出了潜在的干预目标,以改善SAP的结果.

科学领域:

神经学神经学
关键护理医学关键护理医学
传染性疾病传染性疾病

背景情况:

与中风相关的肺炎 (SAP) 是中风的常见并致命的并发症.
国家早期预警分数 (NEWS) 用于评估急性病患者,但其与SAP死亡率的关联尚未得到充分理解.
在SAP中早期识别死亡风险因素对于及时干预至关重要.

研究的目的:

调查NEWS 2评分及其组件与SAP患者死亡时间之间的关联.
为了确定生理变量是否预测SAP患者在抗生素治疗前的死亡率.

主要方法:

分析了389名在入院7天内被诊断患有SAP的患者队列.
使用卡普兰-梅尔生存曲线和多变量考克斯回归模型来评估NEWS 2参数对死亡率的影响.
分析考虑了预先规定的潜在混因素.

主要成果:

死亡率很高,一年后为52.4%,五年后为65.8%.
增加的呼吸速率 (HR1.04,95% CI1.01-1.08,p=0.009) 独立地与死亡时间相关.
较高的NEWS 2总得分 (HR 1.13,95% CI 1.06-1.21,p < 0.001) 也独立地与死亡风险增加有关.

结论:

在开始服用抗生素之前,呼吸率升高和总NEWS 2得分是SAP中死亡率的重要独立预测因素.
这些发现表明,NEWS 2参数可以帮助风险分层,并指导SAP中的处理决策.
需要进一步的研究来探索针对这些生理标志物的干预措施,以改善SAP患者的治疗结果.

关键词:

抗生素抗生素是一种抗生素.脑内出血脑内出血缺血性中风缺血性中风肺炎是一种肺炎.与中风相关的肺炎.

更多相关视频

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model

Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model

Published on: January 6, 2011

相关概念视频

Pneumonia III: Complications and Assessment

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:

Pneumonia I: Introduction

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...

Pneumonia IV: Management

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

Acute Coronary Syndrome III: Diagnostic studies

Acute Coronary Syndrome III: Diagnostic studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...