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Updated: Jun 10, 2025

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在商用塔克罗利木斯无形配方中药物晶度的变化导致可变的药理动力学

Lynne S Taylor1, Niraj S Trasi1, Hitesh S Purohit2

  • 1Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, West Lafayette, IN 47907, United States.

Journal of pharmaceutical sciences
|October 16, 2024
PubMed
概括

药物结晶性显著影响着塔克罗利斯的药理动力学. 即使在通用囊中含有少量晶体塔克罗利斯,也会导致生物等价性失败,这引起了对无形药物配方的临床担忧.

关键词:
没有形态的无形.生物可用性 生物可用性生物等价性 生物等价性结晶性是指结晶性是指结晶性.一般的药物是一般的药物.难溶性 难溶性 难溶性

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