基于先进的酸盐技术的微量矿物质通过调节NF-kB和Nrf2通路来降低Eimeria感染的肉的炎症和氧化应激
Nasim Biabani1, Kamran Taherpour2, Hossein Ali Ghasemi3
1Department of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran.
Scientific reports
|October 16, 2024
概括
在 brojiler料中用基于先进合物技术的矿物质取代无机微量矿物质,改善了生长和对Eimeria感染的免疫力. 以先进的酸盐技术为基础的矿物质进行完全替代,提供了卓越的抗氧化功效和矿物质的可用性.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 动物营养 动物营养
- 免疫学 免疫学 免疫学
背景情况:
- 无机微量矿物质 (ITM) 是必不可少的,但可能存在生物可用性问题.
- 基于先进的酸盐技术的微量矿物质 (ACTM) 提供了更好的吸收和利用.
- 艾梅里亚物种感染会对 brojler 的表现和健康产生负面影响.
研究的目的:
- 评估在 brojler 食中用 ACTM 代替 ITM 的疗效.
- 评估对生产绩效,新陈代谢概况和免疫力的影响.
- 研究与炎症和氧化应激相关的关键信号通路的调制.
主要方法:
- 480只雄性肉被分为五组:负控制,感染的阳性控制,用沙利诺米辛的阳性控制,以及两组50%和100%的ACTM替代.
- 在第14天,被用混合的Eimeria物种卵囊口服.
- 分析了生产性表现,代谢参数,幽默免疫,抗氧化状态和基因表达 (NF-kB,Nrf2通路).
主要成果:
- 阳性对照组与负面对照组相比,表现和免疫标志物降低.
- 在ACTM100组中,体重增加,尸体产量,料效率和矿物质含量 (铁,,铜,) 均有所改善.
- ACTM100增强了抗氧化能力和酶活性,同时降低了氧化应激标志物,其性能和抗炎作用与沙利诺米辛相当.
结论:
- 用ACTM (ACTM100) 完全替代ITM有效地保护肉免受Eimeria感染.
- 在生产性表现和抗炎反应方面,ACTM100显示出与沙利诺米相比的好处.
- 在肉中,ACTM100提供了卓越的抗氧化反应和增强的矿物质生物可用性.
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