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Binu V John¹, Dustin Bastaich², Bassam Dahman²

¹Division of Gastroenterology and Hepatology, Miami VA Medical System, and Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA.

Pharmacoepidemiology and drug safety

|October 16, 2024

概括

对于一次性胆道胆炎 (PBC) 和肝硬化的行政代码具有中等的准确性. 将门高血压和ursodeoxycholic acid (UDCA) 的代码结合起来,可以更好地识别患有肝硬化和PBC的患者.

科学领域:

肝病学肝病学是一种肝病学.
医疗信息学医疗信息学
临床流行病学临床流行病学

背景情况:

通过使用行政代码准确识别患有初级胆管胆道炎 (PBC) 和肝硬化患者是具有挑战性的.
历史名称"初级胆汁硬化"可能导致编码不准确.
本研究评估了国际疾病分类 (ICD) 对PBC和肝硬化病的代码的积极预测值 (PPV).

研究的目的:

确定ICD 9/10代码的准确性,用于识别患有原发性胆道胆炎 (PBC) 和肝硬化患者.
评估结合特定诊断代码对PPV对PBC和肝硬化的影响.

主要方法:

使用VA企业数据仓库的数据进行了一项回顾性队列研究.
用PBC和肝硬化的ICD9或10代码来识别患者.
代码的准确性通过图表审查来验证.

主要成果:

仅使用ICD 9/10代码来识别PBC和肝硬化,PPV为0.52.
结合门高血压的代码,肝硬化病的PPV提高到0.92,PBC肝硬化病的PPV提高到0.64.
将门高血压和ursodeoxycholic acid (UDCA) 的代码结合起来,进一步细化了PPVs:肝硬化 (0.91),PBC (0.78) 和PBC肝硬化 (0.69).

结论:

ICD 9/10代码显示,在一个大型的国家队列中,对于识别PBC和肝硬化患者的可靠性有限.
检测肝硬化的PPV可以通过包括ICD 9/10码用于门高血压和UDCA治疗来显著增强.

关键词:

图表验证的验证图表验证研究结果研究结果研究.门高血压门高血压一次性胆道胆道炎.原发性胆道肝硬化是什么意思

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