精神分裂症患者自杀死亡率的性别相关性:一项为期9年的基于人口的研究
Zihua Pan1,2, Liang Zhou3,4, Yanan Chen1,2
1The Affiliated Brain Hospital, Guangzhou Medical University, 36 Mingxin Road, Liwan District, Guangzhou, 510370, China.
BMC psychiatry
|October 16, 2024
概括
在精神分裂症中,自杀风险因性别而异. 女性患者面临更高的风险,因为缺乏保险或先前的自杀企图,而男性的风险较低,因为晚期发病和住院. 预防必须考虑这些性别特异性因素.
科学领域:
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 精神分裂症显著增加死亡风险,主要是由于自杀.
- 关于精神分裂症患者的性别特异性自杀风险因素的研究有限.
- 了解这些差异对于有针对性的自杀预防策略至关重要.
研究的目的:
- 研究与男性和女性精神分裂症患者自杀死亡率相关的社会人口统计学和临床因素.
- 确定这一群体中性别特定的自杀风险和保护因素.
主要方法:
- 利用来自中国广州33080名精神分裂症患者的数据 (2013-2021年) 来自国家精神病信息系统 (NISP).
- 采用考克斯回归和细灰模型来分析自杀死亡率的社会人口统计和临床相关性.
- 研究了自杀死亡的性别特异性风险因素.
主要成果:
- 总体而言,男性的自杀死亡率 (163.25/100,000) 比女性 (133.89/100,000) 高.
- 对于女性来说,风险因素包括缺乏保险,未接受过治疗的病史和以前的自杀行为.
- 对于男性来说,保护因素包括35-54岁,一次住院和晚期发病年龄 (>28岁).
- 两种性别的风险较低,年龄较大 (≥55) 和多次住院,但结婚或居住在农村地区的风险更高.
结论:
- 性别特定的因素显著影响精神分裂症中自杀风险.
- 对精神分裂症的自杀预防计划应量身定制,以解决这些性别差异.
- 需要进一步的研究来验证这些初步发现.
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