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Updated: Jun 10, 2025

Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies
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在神经损伤后,体外周围神经中细胞变化的单细胞分析

Li Zhao1, Chunyi Jiang1, Bin Yu1

  • 1Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Frontiers in pharmacology
|October 17, 2024
PubMed
概括

单细胞分析揭示了对外围神经损伤的多种细胞反应. 了解神经元,质细胞和免疫细胞中的这些分子变化是开发有效的神经再生疗法的关键.

关键词:
背部根系团的结节.周围神经受伤的情况周围神经系统 周围神经系统坐骨神经的坐骨神经神经.一个单细胞测序.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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