信息的内在价值在小鼠轨道前皮层中的表示
Jennifer J Bussell1,2, Ryan P Badman3,4, Christian D Márton3
1Department of Neuroscience, Columbia University; New York, NY, 10027, USA.
bioRxiv : the preprint server for biology
|October 17, 2024
概括
小鼠表现出寻求信息的内在动机,即使它不会影响奖励. 它们的轨道前皮层 (OFC) 显示出明显的神经活动,代表信息的价值与水等有形奖励.
科学领域:
- 神经科学是一个神经科学.
- 动物行为 动物行为
- 认知科学 认知科学
背景情况:
- 动物经常寻求信息,这表明它具有超越直接奖励的固有价值.
- 了解信息搜索的神经基础对于理解更高的认知功能至关重要.
研究的目的:
- 为了调查小鼠是否对信息有内在的价值.
- 探索大脑中信息估值背后的神经机制.
- 建立一个模型系统来研究信息价值的表示.
主要方法:
- 开发了一个基于气味的任务,小鼠可以选择接收信息.
- 利用微内镜来记录轨道前皮层 (OFC) 中的神经活动.
- 应用了潜在变量模型来分析神经元群体动态.
主要成果:
- 小鼠积极寻找信息,即使它没有改变奖励结果.
- 小鼠愿意放弃水奖励以获得信息.
- 在OFC中,不同的神经元群体对预测信息与水奖励的线索做出了反应.
- OFC活动动态反映了信息价值和水奖励价值的单独表示.
结论:
- 小鼠具有获得知识的内在动力,这表明信息具有内在价值.
- 在OFC中,单独的神经路径代表了信息的内在价值和奖励的外在价值.
- 鼠标作为一个有价值的模型来研究信息价值的神经表征.
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