通过E3结合酶TRIM3737对MTOCs的中层调节

Zhong Y Yeow1, Sonia Sarju1, Mark V Breugel2

  • 1Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

概括

E3酶TRIM37通过控制蛋白质组合来调节细胞分裂. 它的酶活性由基质聚类激活,揭示了TRIM蛋白调节的保存机制.

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