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Updated: May 5, 2026

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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工程化年龄模拟乳腺癌模型揭示了年轻和年长微环境中药物反应的差异

Jun Yang1, Lauren Hawthorne2,3, Sharon Stack4,5

  • 1Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.

bioRxiv : the preprint server for biology
|October 17, 2024
PubMed
概括

这项研究引入了一个模仿年龄的乳腺癌模型,以更好地了解衰老.

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相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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