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Updated: Jun 10, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

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抑制雄激素受体暴露在前列腺癌中的复制应激脆弱性

Carly S Williams, Xin Li, Hongjun Jang

    bioRxiv : the preprint server for biology
    |October 17, 2024
    PubMed
    概括

    转移性前列腺癌的雄激素受体通路抑制剂 (ARPI) 导致DNA复制压力. 将恩扎胺与转化DNA合成抑制剂JH-RE-06结合起来,通过利用这种脆弱性,有效抑制瘤生长.

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