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Updated: Jun 10, 2025

A Drosophila In Vivo Injury Model for Studying Neuroregeneration in the Peripheral and Central Nervous System
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A Drosophila In Vivo Injury Model for Studying Neuroregeneration in the Peripheral and Central Nervous System

Published on: May 5, 2018

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Dnajc3 (HSP40) 增强了老鼠视神经中的轴突再生

Jiaxing Wang, Ying Li, Felix L Struebing

    bioRxiv : the preprint server for biology
    |October 17, 2024
    PubMed
    概括

    这项研究确定Dnajc3是增强光神经受伤后轴突再生的关键基因. 调节Dnajc3水平改善了再生轴突的数量和距离,这表明它有可能恢复人类.

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    Investigating Mammalian Axon Regeneration: In Vivo Electroporation of Adult Mouse Dorsal Root Ganglion06:17

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    Genetic Study of Axon Regeneration with Cultured Adult Dorsal Root Ganglion Neurons

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    相关概念视频

    Neurogenesis and Regeneration of Nervous Tissue01:15

    Neurogenesis and Regeneration of Nervous Tissue

    In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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