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Updated: May 3, 2026

The Multi-organ Chip - A Microfluidic Platform for Long-term Multi-tissue Coculture
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器官芯片技术:机遇和挑战

Santosh Kumar Srivastava1,2,3, Guo Wei Foo1,2,4,3, Nikhil Aggarwal1,2,3

  • 1NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), National University of Singapore, Singapore.

Biotechnology notes (Amsterdam, Netherlands)
|October 17, 2024
PubMed
概括

器官在芯片 (OOC) 技术为生物医学研究和药物查提供先进的体外模型. 本综述将OOC与传统方法进行比较,强调它们在彻底改变生理学研究方面的潜力.

关键词:
2D/3D培养模型在芯片上的肠道在芯片上的脏.在芯片上的肝脏.在芯片上的肺.微流体学 微流体学芯片上的器官 (OOC)

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iChip01:24

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...
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