移植脏质病:表现,管理和跟踪与对照组进行比较
Maxwell Sandberg1, Adam Cohen1, Megan Escott1
1Department of Urology Atrium Health Wake Forest Baptist Medical Center Winston-Salem North Carolina USA.
BJUI compass
|October 17, 2024
概括
结石影响1.4%的移植接受者. 虽然移植存活率相似,但石头患者的移植存活时间更长,这表明需要进一步研究与移植相关的石头形成.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 移植医学 移植医学
背景情况:
- 脏移植后的结石形成是一个公认的并发症.
- 了解这些结石的发生率,风险因素和结果对于患者管理至关重要.
研究的目的:
- 分析结石的表现,管理和长期结果.
- 为了确定与脏移植接受者的结石形成相关的风险因素.
主要方法:
- 一个机构移植数据库的回顾性分析.
- 包括8835名患者,其中128名形成结石,与164名年龄和性别匹配的对照进行比较.
- 使用计算机断层扫描 (CT) 成像对结石进行诊断和尺寸测量.
主要成果:
- 观察到石的低发病率为1.4%,平均识别时间为6.2年.
- 与对照组相比,形成结石的患者表现出较低的血清,减少估计的淋巴细胞过率,更高的淋巴细胞计数和尿路感染率的增加.
- 移植失败率相似,但石头形成者表现出显著更长的移植存活时间.
结论:
- 在移植患者中,结石的形成很少发生,但需要注意.
- 治疗成功率因手术不同而有所不同,皮肤穿神经切除术 (PCNL) 的成功率最低.
- 尽管移植失败率相似,但科石患者的移植存活时间有所改善,需要进一步调查.
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