新生儿脑病多器官评分系统:系统性审查
Noor Adeebah Mohamed Razif1, Aidan D'Arcy1, Sarah Waicus1
1Discipline of Pediatrics, Trinity College Dublin, The University of Dublin, Dublin, Ireland.
Frontiers in pediatrics
|October 17, 2024
概括
新生儿脑病变 (NE) 多器官功能障碍 (MOD) 评分系统显示出显著的异质性. 一个标准化的系统应该包括神经,,肝,呼吸,血液和心血管评估新生儿.
科学领域:
- 新生儿医学 新生儿医学
- 儿科神经学 儿科神经学
- 关键的护理关键的护理
背景情况:
- 新生儿脑病变 (NE) 是一种严重的疾病,导致新生儿多器官损伤.
- 治疗性低温 (TH) 是标准的治疗方法,但在NE中评估多器官功能障碍 (MOD) 的严重程度仍然具有挑战性.
- 目前对NE中MOD评估的方法缺乏标准化.
研究的目的:
- 确定目前用于评估新生儿脑病变 (NE) 中多器官功能障碍 (MOD) 的方法.
- 根据对现有文献的系统审查,确定NE中MOD的最佳评分系统.
主要方法:
- 按照PRISMA指南进行了系统审查.
- 在多个数据库 (PubMed,EMBASE,MEDLINE,Cochrane,Scopus,CINAHL) 进行了搜索,以研究东北地区的MOD评分系统.
- 从12项纳入研究中提取和分析了数据.
主要成果:
- 五项研究表明,NE严重程度和MOD之间存在正相关性.
- 在评分系统中,在资格标准,器官系统评估方法,随访持续时间和结果方面观察到显著的异质性.
- 神经系统,肝脏系统,心血管系统,呼吸系统,血液系统和脏系统通常都被包括在内,而胃肠系统则不太常见.
结论:
- 一个理想的NE多器官评分系统应该包括神经系统,脏系统,肝脏系统,呼吸系统,血液系统和心血管系统.
- 尽管异质,这些系统提供了标准化NE中MOD评分的候选人.
- 需要进一步验证和考虑治疗性低温的影响.
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