在COPD吸入器治疗试验中基于种族的肺功能测试纠正:系统性审查
Jean Z Wang1,2, Ryan Chow1, Sheojung Shin1,2
1Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
International journal of chronic obstructive pulmonary disease
|October 17, 2024
概括
在慢性阻塞性肺病 (COPD) 研究的肺功能测试 (PFT) 中基于种族的校正可能会排除少数群体. 在试验中对基于种族的纠正进行不一致的报道有助于种族化人口的代表性不足.
科学领域:
- 肺部医学 肺部医学
- 临床试验方法论 临床试验方法论
- 健康差异 在健康上的差异
背景情况:
- 基于种族的纠正是肺功能测试 (PFT) 的临床环境中常见的做法.
- 人们担心这种做法可能导致少数群体的诊断不足和被排除在研究之外.
- 本系统性审查调查了基于种族的校正在慢性阻塞性肺病 (COPD) 研究中的使用和影响.
结论:
- 在主要的COPDRCT中,基于种族的纠正可能很普遍,但报告不一致.
- 这种缺乏透明度可能会加剧种族化人口在临床研究中的代表性不足.
- 进一步调查基于种族的纠正对COPD健康平等的影响是有必要的.
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