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Updated: Jun 10, 2025

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
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Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Published on: September 20, 2016

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对c[D-Trp-Phe-β-Ala-β-Ala]的鉴定,这是第一个 κ-阿片类受体特异性的负基调节器

Junwei Zhao1, Monica Baiula2, Elisabetta Cuna2

  • 1Dept. of Chemistry "G. Ciamician", University of Bologna, Campus Navile - Ue4, via Gobetti 83, Bologna 40129, Italy.

ACS pharmacology & translational science
|October 17, 2024
PubMed
概括

研究人员开发了一种新型化合物,专门向卡帕阿片类受体 (KOR). 这种特定于KOR的负基调制剂具有治疗成和神经精神疾病的潜力.

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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission07:16

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