开发和多国验证一套深度学习算法,用于检测和预测结构性心脏病,使用噪音单导电心电图
Arya Aminorroaya1, Lovedeep S Dhingra1, Aline Pedroso Camargos1
1Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
medRxiv : the preprint server for health sciences
|October 17, 2024
概括
一个新的AI算法ADAPT-HEART,使用可穿戴设备的单导电心电图来检测结构性心脏病 (SHD) 并预测未来的风险. 这为社区查和风险分层提供了一个可扩展的方法.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医疗器械 医疗器械
背景情况:
- 12导电心电图人工智能显示出用于检测结构性心脏病 (SHD) 的前景.
- 目前的AI-ECG工具在社区查方面存在局限性.
- 来自可穿戴设备的单线电图为更广泛的可访问性提供了潜力.
研究的目的:
- 开发和验证一种耐噪声,单线AI-ECG算法用于SHD检测.
- 评估算法的预测未来SHD风险的能力.
- 使用便携式设备实现SHD查和风险分层.
主要方法:
- 开发了ADAPT-HEART,这是一种使用266,740个I型心电图的深度学习算法.
- 定义的SHD为LVEF<40%,中度/严重的左侧膜疾病,或严重的LVH.
- 在外部医院站点和ELSA-巴西队列中验证了ADAPT-HEART,并在英国生物银行评估了预测性能.
主要成果:
- ADAPT-HEART在检测SHD方面表现强 (AUROC 0.879在开发中,在外部验证中一致).
- 该算法显示了SHD检测的良好校准.
- 在没有基线SHD的个体中,高ADAPT-HEART概率显著增加了未来的SHD风险 (2.8至5.7倍).
结论:
- 一个新的AI模型检测和预测来自杂的单导电心电图的SHD.
- 该算法适用于便携式/可穿戴设备.
- 这为基于社区的SHD查和风险分层提供了一个可扩展的战略.
相关概念视频
01:28Electrocardiogram Fundamentals
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Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
540
01:29Electrocardiogram
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An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
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01:30Pulse rhythm
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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
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01:30Dysrhythmias V: Evaluating Dysrhythmias
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Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
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