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Updated: Jun 10, 2025

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
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新的4'-功能化双二烯鲁丁复合物的合成,特征和生物活性:抗炎活性进展

Mohamed M Elnagar1,2, Khaled S Abou-El-Sherbini2, Safia Samir3

  • 1Institute of Electrochemistry, Ulm University, Albert-Einstein-Allee 47, 89081, Ulm, Germany.

ChemMedChem
|October 17, 2024
PubMed
概括

新的复合物与双胺联体显示出显著的抗炎,抗癌和抗菌活性. 这些化合物显示出治疗潜力,毒性低于标准药物,突出其生物医学应用.

关键词:
这是一种抗癌药物.抗炎药物 抗炎药物 抗炎药物抗微生物药物是一种抗菌剂.生物活动是生物活动.鲁 (II) 复合体是一个复合体.二二二二二二二二二二二

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ortho–para-Directing Activators: –CH3, –OH, –⁠NH2, –OCH301:11

ortho–para-Directing Activators: –CH3, –OH, –⁠NH2, –OCH3

All ortho–para directors, excluding halogens, are activating groups. These groups donate electrons to the ring, making the ring carbons electron-rich. Consequently, the reactivity of the aromatic ring towards electrophilic substitution increases. For instance, the nitration of anisole is about 10,000 times faster than the nitration of benzene. The electron-donating effect of the methoxy group in anisole activates the ortho and para positions on the ring and stabilizes the corresponding...
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