儿童感染Chromobacterium violaceum:两个病例报告和文献综述
ZhiHong Jiang1, YiFan Ren1, Sheng Ye2
1Department of Paediatrics, ShaoXing KeQiao Women And Children's Hospital, ShaoXing, China.
概括
儿童感染Chromobacterium violaceum的情况罕见但危险. 早期诊断和适当的治疗,如严重病例的西普洛素,对于改善儿科患者的生存率至关重要.
科学领域:
- 医学微生物学 医学微生物学
- 儿童传染病 儿童传染病
背景情况:
- 染色体细菌 (Chromobacterium violaceum) (C. violaceum) 是一种格拉姆阴性细菌,人类感染的发病率很低,特别是在儿童中.
- 尽管罕见,但C. violaceum感染的死亡率很高,治疗指南有限.
研究的目的:
- 提高临床医生对儿科患者中C. violaceum感染的认识.
- 促进及时诊断和治疗,从而改善患者的治疗结果,降低死亡率.
主要方法:
- 在过去十年中,英语出版的儿科C. violaceum文献的综合审查.
- 综合有关病原,风险因素,预后指标,临床表现,诊断和治疗策略的信息.
主要成果:
- 对损伤机制,易感因素和预后不良和死亡率的预测因素的分析.
- 目前死亡率,缓解策略,临床表现和新兴诊断和治疗方法的总结.
结论:
- 在出现蜂炎,败血症或内脏的儿童中,应怀疑C. violaceum感染,特别是在皮肤受伤或接触污染的水/土壤后.
- 建议在严重的儿科病例中使用西普罗夫洛克萨;在不严重的病例中可以使用珍塔米辛,trimethoprim/sulfamethoxazole或伊米佩内姆,根据敏感性测试进行调整.
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