心脏手术中的早期死亡率 - 乳酸盐是否重要?
Mohammad Zeeshan Hakim1, Vivek Tewarson1, Sarvesh Kumar1
1Department of Cardiovascular and Thoracic Surgery, King George's Medical University, Lucknow, India.
Brazilian journal of cardiovascular surgery
|October 17, 2024
概括
血清乳酸水平与心脏手术后更长的恢复时间相关. 虽然手术后24小时的乳酸预测死亡率,但它不是一个敏感的指标.
科学领域:
- 心血管外科心血管外科
- 关键护理医学 关键护理医学
- 生物化学 生化学
背景情况:
- 血清乳酸表明组织低 perfusion 和用于心脏手术患者管理.
- 早期死亡率和术后发病率是心脏手术后的关键问题.
研究的目的:
- 为了确定血清乳酸水平与早期死亡率之间的关联.
- 评估心脏手术患者乳酸盐和术后发病率之间的关系.
主要方法:
- 对270名接受心脏手术的患者进行前性队列研究.
- 在多个时间点测量血清乳酸水平:手术前,手术期间,以及手术后长达48小时.
主要成果:
- 早期死亡发生在6.3%的患者中.
- 乳酸和乳酸清除与机械通风持续时间,血管压缩器持续时间和ICU/住院时间相关.
- 手术前的乳酸和24小时后的乳酸是死亡率的独立预测因素.
结论:
- 动脉乳酸和乳酸清除与恢复指标相关 (通风,血管压缩剂,停留时间).
- 乳酸酸可以指导术后治疗决策.
- 乳酸本身并不是死亡率的敏感预测因素.
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