模拟的血液动力学参数和不同的输液设置会影响在注射器更换期间的药物输送:实验室环境中的实验室研究
Alberto Lucchini1, Stefano Elli2, Alessia Burgazzi3
1Direction of Health and Social Professions - Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; General Adult and Pediatric Intensive Care Unit Fondazione IRCCS San Gerardo dei Tintori, University of Milano-Bicocca, Monza, Italy.
Intensive & critical care nursing
|October 17, 2024
概括
注射器的更换可能会导致液体的流失,特别是在某些中央静脉压力和位置. 使用无针连接器可以减少这些事件在关键输注期间.
科学领域:
- 医疗器械 医疗器械
- 临床工程 临床工程 临床工程
- 药理学 药理学是指药理学的学科.
背景情况:
- 输液疗法是重症监护的基石,经常使用注射器用于精确的药物输送.
- 注射器更换是一个复杂的程序,可能会产生不良事件,如液体注射或反流.
研究的目的:
- 为了研究模拟心脏输出对在注射器更换期间流体位移的影响.
- 分析中心静脉压力,垂直位置,载体输注和无针连接器对这些事件的影响.
主要方法:
- 一项基板研究模拟了使用体外电路的心脏输出量为5L/分钟.
- 变量包括的垂直位置 (-50厘米到+50厘米),中心静脉压 (-5到15毫米),载体输液和无针连接器.
主要成果:
- 中心静脉压力和的垂直位置在更换过程中显著影响了流体位移.
- 流体位移范围从-262到156μL,平均值为8±40μL.
- 在存在载体输液时,无针头装置减少了位移.
结论:
- 注射器的更换是一个关键时刻,特别是在服用血管活性药物时.
- 中枢静脉压力和位置是影响玻尿酸/逆流事件的关键因素.
- 无针系统显示出缓解这些关键的输液相关现象的潜力.
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