在三阴性乳腺癌中,IRE1α静止dRNA,以防止高素激素诱导的热致死

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Updated: Jun 10, 2025

Bacterial Delivery of RNAi Effectors: Transkingdom RNAi
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Bacterial Delivery of RNAi Effectors: Transkingdom RNAi

Published on: August 18, 2010

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Longyong Xu1, Fanglue Peng2, Qin Luo1

  • 1Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

Cell
|October 17, 2024
PubMed
概括

在三阴性乳腺癌 (TNBC) 中抑制IRE1α使得纳化疗可触发免疫反应,使得冷瘤对免疫治疗敏感. 这表明IRE1α是癌细胞抵抗化疗的关键因素.

关键词:
紧急救护室的压力其他:患有PD-L1阴性乳腺癌dsRNA 的时间热症

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