运动取消期间肌肉高频神经输入的变化
Blanka Zicher1, Simon Avrillon1, Jaime Ibáñez1,2,3
1Department of Bioengineering and Computing, Imperial College London, London W12 0BZ, United Kingdom.
Journal of neural engineering
|October 17, 2024
概括
运动皮质β和马振荡在动作取消过程中检测到肌肉活动. 肌肉中的这些大脑节奏在没有显著的力变化的情况下发生,这表明对外围神经接口的应用更广泛.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 生物医学工程 生物医学工程
背景情况:
- 皮层β (13-30 Hz) 和 (30-60 Hz) 振荡是运动皮层活动的关键.
- 它们的传递到肌肉和脊髓的影响尚未完全理解,尤其是在运动控制任务期间.
- 现有的知识缺乏洞察这些振荡在脊柱水平的突出性.
研究的目的:
- 为了研究不同运动状态期间发动神经元的高频输入中的调制.
- 在保持稳定的力量的同时,在"GO"/"NO-GO"任务期间检查肌肉活动中的皮质β和马振荡.
- 为了确定肌肉记录是否反映了超出直接力调节的运动状态.
主要方法:
- 使用"GO"/"NO-GO"任务,其中12名参与者执行弹道收缩或取消.
- 使用脑电图 (EEG) 记录大脑活动和通过高密度表面和肌内电肌图 (EMG) 记录肌肉活动.
- 在使用稳定力"NO-GO"试验期间,分析了前肌的运动单元 (MU) 发射活动和光谱含量变化.
主要成果:
- 在"NO-GO"提示之后,在MU群体中观察到β和低马 (30-45Hz) 活性增加,反映了EEG发现.
- 这些光谱变化发生在肌肉力量输出没有显著改变的情况下.
- 证明肌肉活动反映皮质指令的变化,即使力输出受到限制.
结论:
- 运动皮质β和马节奏在"GO"/"NO-GO"任务中的动作取消过程中可以检测到肌肉活动.
- 这些基于肌肉的振荡发生的独立于力量生产的显著变化.
- 肌肉记录提供了对运动状态的洞察力,不仅仅与力量控制有关,突出了外围神经接口的潜力.
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