确定对大麻消费敏感的标准化神经心理测试措施:系统性审查
K B Stefanidis1, C Schiemer1, T Mieran1
1MAIC/UniSC Road Safety Research Collaboration, University of the Sunshine Coast, 90 Sippy Downs Dr, Sippy Downs, Queensland 4556, Australia.
Journal of affective disorders
|October 17, 2024
概括
这次审查发现,特定的神经心理测试,包括CANTAB空间工作记忆,霍普金斯口头学习测试,散文回忆和雷伊听觉口头学习测试,对Δ9-四大麻素 (THC) 的影响敏感. 需要进一步的研究来开发大麻诱导的神经认知障碍的验证措施.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 许多研究表明,在Δ9-四化甘醇 (THC) 给药后,出现了急性神经认知变化.
- 确定对THC效应最敏感的标准化神经心理测试至关重要.
研究的目的:
- 系统地审查关于THC对标准化神经心理测试措施的影响的科学证据 (自2000年以来).
- 为了确定哪些标准化测试对THC最敏感.
主要方法:
- 按照PRISMA指南进行的系统审查.
- 包括使用在受试者之间或在受试者内部设计的研究,以评估THC对神经心理测试绩效的影响.
主要成果:
- 包括12项研究,检查了8项标准化神经心理测试.
- 剑桥神经心理测试自动化电池 (CANTAB) 空间工作记忆子测试,霍普金斯口语学习测试,散文回忆和雷听力口语学习测试对大麻消费敏感.
结论:
- 研究中的实质性变化阻止了定量分析.
- 很少有研究使用标准化的神经心理测量来评估THC.
- 需要对标准化,验证的神经认知功能的测量进行进一步的研究,以开发行为障碍评估.
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