从有前途的研究转变为常规的临床实践:从实施科学领域的经验教训
Danielle R Adams1, Heidi Allen2,3, Ginger E Nicol4
1School of Social Work, College of Health Sciences, University of Missouri-Columbia, Columbia, MO 65211, USA.
Translational behavioral medicine
|October 17, 2024
概括
迷幻药辅助心理治疗 (PAT) 显示出对心理健康状况的前景. 实施科学对于确保在不同的医疗保健环境中公平获得这些新疗法至关重要.
科学领域:
- 精神病学和行为健康
- 实施科学 实施科学
- 公共卫生 公共卫生
背景情况:
- 迷幻药辅助心理治疗 (PAT) 在治疗的同时使用了psilocybin,MDMA和LSD等物质.
- 临床试验表明PAT对PTSD,抑郁症和物质使用障碍的疗效.
- 美国食品和药物管理局预计,到2026年,可以批准治疗抑郁症的 псилоцибин疗法,因此需要制定实施策略.
研究的目的:
- 促进实施科学家和PAT研究人员/从业人员之间的对话.
- 探索实施科学如何加速PAT的转化到实践中.
- 专注于PAT在边缘化人口的安全网设置中的公平整合.
主要方法:
- 使用覆盖范围,有效性,采用,实施和维护 (RE-AIM) 框架.
- 确定实施策略,方法 (例如实用试验) 和方法 (例如CBPR).
- 专注于工具,以确保安全,有效性和可访问性在服务不足的社区.
主要成果:
- RE-AIM框架为评估PAT实施提供了一个结构.
- 实施科学提供了解决现实世界PAT交付挑战的方法.
- 以社区为基础的参与性研究被强调为公平的关键方法.
结论:
- 实施科学对于成功和公平地将PAT整合到日常护理中至关重要.
- 实施科学原则的战略应用可以克服PAT访问的障碍.
- 确保PAT在安全网设置中的可用性对于为历史边缘化人口提供服务至关重要.
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