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Updated: Jul 1, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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顺序响应的纳米-PROTACs用于精确的细胞内传递和增强降解疗效在结肠直肠癌治疗

Liuqing Yang1, Ye Yang1, Jing Zhang1

  • 1Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191, Beijing, China.

Signal transduction and targeted therapy
|October 17, 2024
PubMed
概括

聚合物纳米粒子增强了用于结直肠癌治疗的PROTAC输送. 这些纳米粒子改善瘤透和细胞吸收,导致有效的蛋白质降解和协同抗癌效应,当与免疫检查点抑制剂相结合时.

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